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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS1
All Species:
11.82
Human Site:
Y400
Identified Species:
18.57
UniProt:
O95835
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95835
NP_004681.1
1130
126870
Y400
G
S
A
A
P
S
S
Y
T
N
G
S
I
P
Q
Chimpanzee
Pan troglodytes
XP_001173355
1130
126853
Y400
G
S
A
A
P
S
S
Y
T
N
G
N
I
P
Q
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
L152
L
L
V
H
G
E
P
L
G
Y
G
V
Q
R
S
Dog
Lupus familis
XP_534537
1097
121903
D387
S
S
T
L
S
R
R
D
S
L
Q
K
P
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYR2
1129
126167
F399
A
S
A
A
P
P
S
F
A
N
G
N
V
P
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
Y391
V
P
A
A
P
S
P
Y
A
N
G
T
V
P
Q
Chicken
Gallus gallus
XP_419666
1136
127431
Y406
G
S
A
P
P
S
A
Y
T
N
G
N
L
P
P
Frog
Xenopus laevis
NP_001087838
1118
125984
G395
P
L
S
S
N
A
Y
G
T
N
T
N
L
P
P
Zebra Danio
Brachydanio rerio
NP_001018346
1068
120780
A386
I
R
P
P
V
Q
Q
A
Q
T
P
P
G
Q
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA38
1105
122470
Q389
L
Q
T
A
V
A
P
Q
S
P
S
S
A
S
A
Honey Bee
Apis mellifera
XP_395146
1137
124999
P436
T
T
S
N
T
P
P
P
P
P
S
Y
A
S
S
Nematode Worm
Caenorhab. elegans
Q2L6W9
476
55529
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
Q476
A
G
H
I
G
G
Q
Q
Q
R
G
G
T
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
N99
A
T
P
P
P
H
N
N
Y
A
A
S
N
Q
M
Red Bread Mold
Neurospora crassa
P38679
598
67999
Conservation
Percent
Protein Identity:
100
99.6
35.8
50.9
N.A.
92.8
N.A.
N.A.
80.8
85.2
74.7
63.1
N.A.
38.6
40.2
20.7
38
Protein Similarity:
100
99.8
44.7
63.4
N.A.
96.7
N.A.
N.A.
87.1
92.1
83.4
73.7
N.A.
50.2
52.6
29.6
51.9
P-Site Identity:
100
93.3
6.6
6.6
N.A.
60
N.A.
N.A.
60
66.6
20
0
N.A.
13.3
0
0
13.3
P-Site Similarity:
100
100
6.6
13.3
N.A.
80
N.A.
N.A.
73.3
86.6
53.3
0
N.A.
26.6
13.3
0
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28
24.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
35.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
0
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
0
34
34
0
14
7
7
14
7
7
0
14
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
7
% D
% Glu:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% F
% Gly:
20
7
0
0
14
7
0
7
7
0
47
7
7
7
0
% G
% His:
0
0
7
7
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
7
0
0
0
0
0
0
0
0
14
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% K
% Leu:
14
14
0
7
0
0
0
7
0
7
0
0
14
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% M
% Asn:
0
0
0
7
7
0
7
7
0
40
0
27
7
0
0
% N
% Pro:
7
7
14
20
40
14
27
7
7
14
7
7
7
47
14
% P
% Gln:
0
7
0
0
0
7
14
14
14
0
7
0
7
14
27
% Q
% Arg:
0
7
0
0
0
7
7
0
0
7
0
0
0
7
0
% R
% Ser:
7
34
14
7
7
27
20
0
14
0
14
20
0
14
14
% S
% Thr:
7
14
14
0
7
0
0
0
27
7
7
7
7
0
7
% T
% Val:
7
0
7
0
14
0
0
0
0
0
0
7
14
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
7
27
7
7
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _